Janumet XR Tablets (60)

US $165.00US $166.00

Janumet XR Tablets (60) US $165.00US $166.00
Prescription Required

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Janumet XR

(See detailed Medicine Prescription Information here)

Type of medication
Oral medication.
Assist in
Prescription medication.
Treatment of
Used for
Adults – YES;  Children – No.
Medicine family
The tablet contains two prescription medicines, Sitagliptin and Metformin.
The oral prescription medication Janumet XR Tablets can lower the blood sugar levels of type 2 diabetes in adults. Sitagliptin and Metformin are two prescription drugs found in tablets.

How will the Janumet XR help?

For individuals with type II diabetes. For best results, Janumet XR should be taken in conjunction with a healthy diet and regular exercise to control blood sugar levels.

How does Janumet XR work?

Human body naturally produce insulin. Janumet XR helps your pancreas produce more insulin. Insulin helps regulate blood sugar. Two anti-diabetic medications, Sitagliptin and Metformin, are combined in each tablet to better control your blood sugar.
Sitagliptin is a member of a class of drugs known as DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors), which work to increase the amount of insulin that your body produces when your blood sugar is too high, especially after eating. Additionally, sitagliptin aids in reducing the quantity of sugar your body produces and is less likely to result in hypoglycemia, a typical adverse effect of antidiabetic medications.
Metformin decreases the amount of sugar your liver produces and is a member of the class of drugs known as biguanides.
Together, these medications assist you in achieving your objective of improved blood sugar regulation.

Janumet XR

How to take Janumet XR Medication?

  • The medicine should be taken orally with meal. Doctor will prescribe the dosage of medicine.
  • Janumet drug class should not be taken if you are already prescribed with Metformin or any form of combination of Metformin and Sitagliptin.
  • Junamet XR can be taken with Sulfonylurea medication if you are not already taking Metformin with a Sulfonylurea drug.
  • Junamet XR can be taken with a premixed or long-to-intermediate-acting insulin.
  • Junamet XR can be taken with Pioglitazone only if not currently taking a combination of Metformin and Pioglitazone.
  • Janumet XR should be taken with meals to reduce your risk of experiencing upset stomach.
    Note – Do not cut or break the tablets before consuming; consume them whole. Continue to take Junamet XR as long as your doctor instructs you to. It’s necessary to take each dose as prescribed.

Dosage of Janumet XR

Different people may require a different dosage. Be sure to take your medication exactly as per your doctor instructions. Based on your present lifestyle, your tolerance, and Janumet XR efficacy, your dose will probably be prescribed for you.
The highest daily dose is 2000 mg of metformin and 100 mg of sitagliptin administered orally. A typical dosage for those who are not already taking metformin is 500 mg of metformin and 50 mg of sitagliptin taken twice a day orally. A typical dose for someone is 50mg of sitagliptin in addition to taking metformin is medication, taken orally twice per day. For those who are already on a high daily dose of metformin, 1000Mg of metformin and 50Mg of sitagliptin, taken orally, twice a day, is advised.
Note: Do not alter your medication your doctor has prescribed if you find something different from the ones listed here. It is crucial that you take this medication exactly as your doctor has advised.

Warnings and Precautions while using Janumet XR

Before taking Janumet, inform your doctor if you:

  • Have pancreatitis (inflammation of your pancreas).
  • serious renal issues previously or currently.
  • liver issues previously or currently.
  • have heart issues, such as congestive heart failure, or have had such issues.
  • Drink alcohol frequently or in large quantities in a short period of time (“binge” drinking).
  • Need a dye or contrast agent injection for a scanning or imaging procedure.
  • Have any additional medical issues.
  • are expecting a child or intend to get pregnant. Whether Janumet XR can harm an unborn child is not yet known. Make sure to discuss the best strategy to control your blood sugar levels during pregnancy with your doctor if you are pregnant or intend to become pregnant.
  • are now breastfeeding or intend to. It is unclear if the medication enters breast milk. Consult your physician about the best options for feeding your infant while taking Janumet XR.

Stop taking Janumet XR immediately if you get the following symptoms of lactic acidosis:

  • You feel cold, specifically in your arms and legs.
  • You feel dizzy or lightheaded.
  • You develop a slow or irregular heartbeat.
  • Your medical condition abruptly changes You feel tired and very weak.
  • You have unusual muscle pains.
  • You have problems with breathing.
  • You have stomach pain, along with nausea and vomiting or diarrhea.

Cases of pancreatitis (inflammation of the pancreas), which may be severe and lead to death, have been reported in some patients.

Janumet XR side effects

Common negative effects may include:

  • lactic acidosis
  • stuffy or runny nose, and sore throat
  • upper respiratory infection
  • increased hunger
  • seizures
  • shakiness
  • slurred speech
  • diarrhea
  • Uncommon negative effects may include:
  • anxiety
  • blurred vision
  • chills
  • confusion
  • cool, pale skin
  • dizziness
  • low blood sugar (hypoglycemia) when used in combination with certain drugs, such as insulin or a Sulfonylurea
  • gas, upset stomach, indigestion
  • weakness
  • vomiting and nausea
  • headache
  • fast heartbeat
  • headache

Discuss with your doctor any adverse effect – side effect that bothers you or does not go away. For medical advice about side effects, contact your Doctor

Additional information


50mg/1000mg, 50mg/500mg