About Humulin Insulin R Vials (Regular Insulin)
Humulin Insulin R is a short-acting human insulin available inside Humulin Insulin R Vials. It is used to improve glycemic control in adult and pediatric patients with diabetes mellitus. There are two types of Humulin R insulin:
- Humulin R U-100.
- Humulin R U-500 is a more concentrated insulin.
U-100 insulins, including Humulin Insulin R Vials, contain 100 units per mL. It is available as:
- 10 mL multiple-dose vial
- 3 mL multiple-dose vial
Humulin Insulin R can be injected as a subcutaneous or intravenous injection. Administer Humulin R intravenously only under medical supervision. Humulin R can be diluted with Sterile Diluent for subcutaneous injection only under medical supervision.
What is dosage of Humulin Insulin R?
For Subcutaneous Injection:
- Inject Humulin Insulin R approximately 30 minutes before meals.
- Select the suitable place in the thigh, upper arm, abdomen, or buttocks.
- Keep rotating injection sites to reduce the risk of lipodystrophy and localized cutaneous amyloidosis.
- Do not inject into areas of lipodystrophy or localized cutaneous amyloidosis.
Note: Mixing of Humulin R with another insulin
- HUMULIN Insulin R should be mixed only with HUMULIN Insulin N.
- For proper mixing, draw the Humulin R first into the syringe and Inject immediately after mixing.
Do not use Humulin R U-100:
- If it appears cloudy, thickened, or slightly colored, or
- If solid particles are visible
Warnings and Reactions of Humulin Insulin R
Before using Humulin Insulin R, talk to your doctor if you:
- Have liver or kidney problems.
- Take other medicines, especially ones called TZDs (thiazolidinediones).
- Have heart failure or other heart problems.
- Are pregnant, planning to become pregnant.
- Are you breastfeeding or plan to breastfeed
- About all the medicines you take, including vitamins or herbal supplements.
Never share a syringe or pen while using single-person use syringe or pen when injecting Humulin R with other patients, even if you use a new needle. Monitor your condition each time the doctor changes your dose for hypoglycemia or hyperglycemia. Do not inject Insulin in the same area to prevent lipodystrophy or localized cutaneous amyloidosis.
Symptoms of Hypoglycaemia may include:
- dizziness or light-headedness
- blurred vision
- anxiety, irritability, or mood changes
- slurred speech
- confusion or drowsiness
- fast heartbeat
- feeling jittery
Allergic Reactions of Humulin Insulin R
If using Humulin Insulin R Vials, you must inform your doctor if you find the following symptoms and issues:
- Hypersensitivity Reactions – This may include anaphylaxis, generalized skin reactions, rash, angioedema, bronchospasm, hypotension, and shock.
- Hypokalemia – Humulin R can cause low levels of potassium in your blood.
- Medication Errors – Other insulins that have been accidentally substituted for HUMULIN R have been identified during postapproval use.
- Peripheral Edema – May cause sodium retention and edema
- Weight Gain – Attributed to the anabolic effects of Insulin.
- Immunogenicity – This may cause anti-insulin antibodies to form.
- Injection Site Reactions – This may include injection site hematoma, pain, hemorrhage, erythema, nodules, swelling, discoloration, pruritus, warmth, and injection site mass.
Storage and Usage of Humulin Insulin R
10 mL multiple-dose Humulin Insulin R Vials or 3 mL multiple-dose Humulin Insulin R Vials
- 31 Days – Not in-use – Room Temperature (up to 86°F [30°C])
- Until expiry date – Not in-use – Refrigerated (36° to 46°F[2° to 8°C])
- 31 days or earlier if expired – In use – Room Temperature (up to 86°F [30°C])
- 31 days or earlier if expired – In use – In use Refrigerated (36° to 46°F[2° to 8°C])
Remember that regular physical exercise is crucial to treating diabetes or managing prediabetes, along with your diet planning, weight management, and medications. Because your cells become more responsive to insulin while you are active, your blood glucose, also known as blood sugar, can be lowered more successfully. Take your medications regularly and follow up with your healthcare specialist.